Microfluidic Impedance Flow Cytometry Enabling High-Throughput Single-Cell Electrical Property Characterization
نویسندگان
چکیده
منابع مشابه
Microfluidic Impedance Flow Cytometry Enabling High-Throughput Single-Cell Electrical Property Characterization
This article reviews recent developments in microfluidic impedance flow cytometry for high-throughput electrical property characterization of single cells. Four major perspectives of microfluidic impedance flow cytometry for single-cell characterization are included in this review: (1) early developments of microfluidic impedance flow cytometry for single-cell electrical property characterizati...
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Recent advances in microfluidics and microfabrication techniques have led to a variety of portable and inexpensive lab-on-a-chip devices to make quantitative assays of microscale and nanoscale bioparticles. Among them, electrical impedance flow cytometers have become an indispensable tool in clinical and research laboratories for analysis of micro/nano bio-objects. Because of their simplicity a...
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This paper presents a micro-biosensor based on Electrical Bio-Impedance Spectroscopy (EBIS), applied to blood cells characterization and diagnosis. This sensor uses microfluidic flow, coupled to EBIS system to perform cell by cell measurements at high flow rate, up to several hundred cells per second. Two devices were realized with different materials, SU_8 resin and polydimethylsyloxane PDMS t...
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Single-cell impedance cytometry is a non-invasive method for characterizing individual cells and particles [1, 2]. A microfluidic impedance chip typically consists of a microchannel equipped with microelectrodes and filled with a conductive buffer. An AC voltage is applied to a pair of electrodes, which causes a current to flow between them. The current change upon passage of a cell between the...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2015
ISSN: 1422-0067
DOI: 10.3390/ijms16059804